{"id":11908,"date":"2018-08-19T18:35:32","date_gmt":"2018-08-19T15:35:32","guid":{"rendered":"http:\/\/www.werathah.com\/special\/?p=11908"},"modified":"2018-11-03T17:24:56","modified_gmt":"2018-11-03T14:24:56","slug":"cornelia-de-lange-syndrome-medical","status":"publish","type":"post","link":"https:\/\/www.werathah.com\/special\/disorders\/cornelia-de-lange\/cornelia-de-lange-syndrome-medical\/","title":{"rendered":"\u00a0\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a\u0644\u0627\u0646\u062c-\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0637\u0628\u064a\u0629"},"content":{"rendered":"<h1 style=\"text-align: center;\"><span style=\"color: #33cccc;\"><strong>\u00a0\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a\u0644\u0627\u0646\u062c<\/strong><\/span><\/h1>\n<h3 style=\"text-align: center;\"><span style=\"color: #000000;\">Cornelia De Lange\u00a0 Syndrome<\/span><\/h3>\n<h1 style=\"text-align: center;\"><span style=\"color: #ff0000;\">\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0637\u0628\u064a\u0629<\/span><\/h1>\n<h1 style=\"text-align: center;\"><\/h1>\n<h2 style=\"text-align: right;\"><strong><u><span style=\"color: #33cccc;\">\u0627\u0633\u0645\u0627\u0621 \u0645\u062a\u0631\u0627\u062f\u0641\u0629<\/span><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-565\" src=\"http:\/\/werathah.com\/birth-defects\/wp-content\/uploads\/2018\/03\/cornelia_deLange.jpg\" alt=\"\" width=\"377\" height=\"471\" \/><\/u><\/strong><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0634\u0639\u0631 \u0627\u0644\u0643\u062b\u064a\u0641<\/strong> <strong>Bushy Syndrome\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0642\u0632\u0627\u0645 \u0627\u0645\u0633\u062a\u0631\u062f\u0627\u0645.<\/strong> <strong>Amsterdam dwarfism<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0641\u064a \u0639\u0627\u0645 1916\u0645 <\/strong><strong>\u0646\u0634\u0631 \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u0623\u0644\u0645\u0627\u0646\u064a \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0628\u0631\u0627\u0634\u0645\u0627\u0646 ( <\/strong><strong>Brachmann<\/strong><strong> )\u0648 \u0627\u0644\u0630\u064a \u0639\u0627\u0634 \u0628\u064a\u0646 \u0639\u0627\u0645\u064a (1888-1969 ) \u0645\u0639\u0644\u0648\u0645\u0627\u062a <\/strong><strong>\u0639\u0646 \u00a0\u0634\u0627\u0628 \u0641\u064a <\/strong><strong>\u064a\u0628\u0644\u063a 19 \u0639\u0627\u0645 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u00a0\u0628\u0645\u0644\u0627\u0645\u062d <\/strong><strong>\u0645\u0645\u064a\u0632\u0629 . \u062c\u0627\u0621 <\/strong><strong>\u0645\u0646 <\/strong><strong>\u0628\u0639\u062f\u0647 \u0637\u0628\u064a\u0628<\/strong><strong> \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0627\u0644<\/strong><strong>\u0647\u0648\u0644\u0646\u062f\u064a \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u0643\u0627\u062b\u0631\u064a\u0646\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u00a0\u00a0(<\/strong><strong><a href=\"https:\/\/en.wikipedia.org\/wiki\/Cornelia_Catharina_de_Lange\" target=\"_blank\" rel=\"noopener\">Cornelia Catharina de Lange<\/a><\/strong><strong>) \u0633\u0646\u0629 1933\u00a0 \u0648 \u062f\u0631\u0633 \u0647\u0630\u0647 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0648 \u0633\u0645\u064a\u062a \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0628\u0623\u0633\u0645\u0647 . \u0644\u0630\u0644\u0643 \u0641\u0627\u0644\u0627\u0633\u0645 \u0627\u0644\u0635\u062d\u064a\u062d <\/strong><strong>\u0644\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 <\/strong><strong>\u0647\u0648 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0628\u0631\u0627\u0634\u0645\u0627\u0646 \u062f\u064a \u0644\u0627\u0646\u062c. <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u0647\u064a \u062d\u0627\u0644\u0629 \u0648\u0631\u0627\u062b\u064a <\/strong><strong>\u062a\u0633\u0628\u0628 \u0627\u0644\u0639\u062f\u064a\u062f<\/strong><strong> \u0645\u0646 \u0627\u0644\u0627\u0639\u0631\u0627\u0636 <\/strong><strong>\u0627\u0644\u062c\u0633\u0645\u064a\u0629 <\/strong><strong>\u0648 \u0627\u0644\u0645\u0639\u0631\u0641\u064a\u0629 \u0648 \u0627\u0644\u0635\u062d\u064a\u0629. <\/strong><strong>\u0648\u0647\u064a <\/strong><strong>\u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0643\u0644\u0627 \u0627\u0644\u062c\u0646\u0633\u064a\u0646 \u0628\u0627\u0644\u062a\u0633\u0627\u0648\u064a .\u0648\u062a\u0635\u064a\u0628 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0639\u0631\u0627\u0642 \u0648 \u0627\u0644\u0623\u062c\u0646\u0627\u0633 . <\/strong><strong>\u0648\u062a\u0635\u064a\u0628 <\/strong><strong>\u062a\u0642\u0631\u064a\u0628\u0627\u064b \u00a0<\/strong><strong>\u0637\u0641\u0644 \u0648\u0627\u062d\u062f <\/strong><strong>\u0645\u0646 \u0643\u0644 <\/strong><strong>10 \u0627\u0644\u0627\u0644\u0641 \u0627\u0644\u0649 30 \u0627\u0644\u0641 \u0637\u0641\u0644 \u0645\u0648\u0644\u0648\u062f . <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0647\u0646\u0627\u0643 \u0646\u0648\u0639 \u0643\u0644\u0627\u0633\u064a\u0643\u064a \u0645\u0646 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c\u00a0 \u0648 \u0646\u0648\u0639 <\/strong><strong>\u062e\u0641\u064a\u0641<\/strong><strong>. \u0645\u0639\u0638\u0645 \u0627\u0644\u0635\u0641\u0627\u062a <\/strong><strong>\u0627\u0644\u062c\u0633\u0645\u064a\u0629 <\/strong><strong>\u0648 \u0627\u0644\u0641\u0643\u0631\u064a\u0629 \u0648 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0633\u0644\u0648\u0643\u064a\u0629\u00a0 \u062a\u0635\u0646\u0641 \u0645\u0646 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0643\u0644\u0627\u0633\u064a\u0643\u064a \u0648 \u0627\u0630\u0627 \u0643\u0627\u0646\u062a <\/strong><strong>\u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0623\u062e\u0641 <\/strong><strong>\u062a\u0635\u0646\u0641 \u062a\u062d\u062a \u0627\u0644\u0646\u0648\u0639 <\/strong><strong>\u0627\u0644\u062e\u0641\u064a\u0641 <\/strong><strong>.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0627\u0644\u0623\u0634\u062e\u0627\u0635 <\/strong><strong>\u0645\u0646 \u0630\u0648\u064a <\/strong><strong>\u0645\u062a\u0644\u0627\u0632\u0645\u0629 <\/strong><strong>\u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627\u00a0 \u062f\u064a \u0644\u0627\u0646\u062c <\/strong><strong>\u064a\u062a\u0634\u0627\u0628\u0647\u0648\u0646 \u0628\u064a\u0646 \u0628\u0639\u0636\u0647\u0645 \u0627\u0644\u0628\u0639\u0636 \u0647\u0630\u0627 \u0627\u0644\u062a\u0634\u0627\u0628\u0647 \u0644\u0627 \u064a\u0643\u0648\u0646 \u0628\u0634\u0643\u0644 \u0643\u0628\u064a\u0631 \u0639\u0646\u062f \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0627\u0644\u0644\u0630\u064a\u0646 \u064a\u0635\u0646\u0641\u0648\u0646 \u0628\u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0645\u0639\u062a\u062f\u0644 .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><strong>\u0648 \u0645\u0639 \u062a\u0642\u062f\u0645 \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0627\u0635\u0628\u062d \u0628\u0627\u0644\u0625\u0645\u0643\u0627\u0646 \u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0648 \u0644\u064a\u0633 \u0644\u062f\u064a\u0647\u0627 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062a\u064a \u0633\u0646\u0630\u0643\u0631\u0647\u0627\u00a0 \u060c\u0643\u0645\u0627 \u0623\u0646 \u062a\u0623\u062b\u064a\u0631\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0642\u062f\u0631\u0627\u062a \u0627\u0644\u0641\u0643\u0631\u064a\u0629 \u0648 \u0627\u0644\u0633\u0644\u0648\u0643\u064a\u0629 \u0627\u064a\u0636\u0627\u064b \u0645\u062a\u0641\u0627\u0648\u062a\u0629 .<\/strong><strong> \u0647\u0630\u0627 \u0628\u0633\u0628\u0628 \u0627\u0644\u0635\u0641\u0627\u062a <\/strong><strong>\u0627\u0644\u062c\u0633\u0645\u064a\u0629 <\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u0627\u0644\u0623\u0639\u0631\u0627\u0636<\/strong><\/span><\/h1>\n<p style=\"text-align: right;\"><strong>\u0630\u0648\u064a \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u064a\u062a\u0634\u0627\u0628\u0647\u0648\u0646 \u0628\u0634\u0643\u0644 \u0642\u0648\u064a \u0628\u064a\u0646 \u0628\u0639\u0636\u0647\u0645 \u0627\u0644\u0628\u0639\u0636 \u0648 \u0630\u0644\u0643 \u0644\u062a\u0634\u0627\u0628\u0647\u0647\u0645 \u0641\u064a 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\u0627\u0644\u0642\u0627\u0645\u0629 \u0648 \u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0644\u0627\u062d\u064a\u0627\u0646 \u0627\u0644\u064a\u062f\u064a\u0646<\/strong><\/li>\n<li><strong>\u0645\u0634\u0627\u0643\u0644 \u062e\u0644\u0642\u064a\u0629 \u0641\u064a \u0627\u0644\u0642\u0644\u0628<\/strong><\/li>\n<\/ul>\n<p style=\"text-align: right;\"><strong>\u0647\u0646\u0627\u0643 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0627\u0644\u062c\u0633\u0645\u064a\u0629 \u0648\u0627\u0644\u062a\u063a\u064a\u0631\u0627\u062a \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0644\u062d\u0627\u0644\u0629\u060c \u0648\u0644\u0643\u0646 \u0644\u064a\u0633 \u0645\u0646 \u0627\u0644\u0645\u0641\u062a\u0631\u0636 \u0648\u062c\u0648\u062f \u062c\u0645\u064a\u0639 \u062a\u0644\u0643 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0641\u064a \u0643\u0644 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u062d\u0627\u0644\u0629\u060c \u0648\u0641\u064a \u0645\u0627 \u064a\u0644\u064a \u0633\u0646\u0648\u062c\u0632 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0627\u0644\u0645\u062a\u0643\u0631\u0631\u0629 \u0641\u064a \u0623\u063a\u0644\u0628 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0648\u0645\u0646\u0647\u0627<\/strong><strong>:<\/strong><\/p>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u00a0\u0642\u0627\u0626\u0645\u0629 \u0628\u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u0623\u0643\u062b\u0631 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b:<\/strong><\/span><\/h2>\n<ul style=\"text-align: right;\">\n<li><span style=\"color: #000000;\"><strong>\u0635\u063a\u0631 \u0627\u0644\u0628\u0646\u064a\u0629 \u0645\u0639 \u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0648\u0632\u0646 \u0648 \u0627\u0644\u0637\u0648\u0644 \u0648 \u0645\u062d\u064a\u0637 \u0627\u0644\u0631\u0623\u0633 \u0639\u0646\u062f \u0627\u0644\u0648\u0644\u0627\u062f\u0629<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0642\u0635\u0631 \u0627\u0644\u0627\u0637\u0631\u0627\u0641 \u062e\u0627\u0635\u0629 \u0627\u0644\u0639\u0644\u0648\u064a\u0629 \u0645\u0646 \u062a\u0634\u0648\u0647\u0627\u062a \u0628\u062f\u0631\u062c\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u0646 \u0637\u0628\u064a\u0639\u064a \u0627\u0644\u0649 \u0646\u0642\u0635 \u0634\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u0627\u0637\u0631\u0627\u0641.<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0636\u0639\u0641 \u0627\u0644\u0631\u0636\u0627\u0639\u0629 \u0644\u062f\u0649 \u0627\u0644\u0645\u0648\u0627\u0644\u064a\u062f<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u062d\u0648\u0627\u062c\u0628 <\/strong><strong>\u0643\u062b\u064a\u0641\u0647 <\/strong><strong>\u0648 <\/strong><strong>\u0645\u0644\u062a\u0635\u0642\u0647 <\/strong><strong>\u0628\u0627\u0644\u0645\u0646\u062a\u0635\u0641<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0631\u0645\u0648\u0634 \u0637\u0648\u064a\u0644\u0629 \u0648 \u0634\u0639\u0631 \u062c\u0633\u0645 \u0643\u062b\u064a\u0641<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0627\u0646\u0641 \u0642\u0635\u064a\u0631 \u0645\u0631\u0641\u0648\u0639 \u060c\u0648 \u0634\u0641\u0627\u0647 \u0631\u0641\u064a\u0639\u0629 \u0648 \u0645\u0642\u0644\u0648\u0628\u0629 \u0644\u0644\u0623\u0633\u0641\u0644 \u060c\u0648 \u0623\u0633\u0646\u0627\u0646 \u0635\u063a\u064a\u0631\u0629 \u0648 \u0645\u062a\u0641\u0631\u0642\u0629<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0635\u0639\u0648\u0628\u0627\u062a \u0641\u064a \u0627\u0644\u0646\u0638\u0631 \u0648\u0642\u062f \u064a\u062d\u062a\u0627\u062c \u0627\u0644\u0649 \u0646\u0638\u0627\u0631\u0629 \u0637\u0628\u064a\u0629 <\/strong><strong>\u060c\u0643\u0642\u0635\u0631 \u0627\u0644\u0646\u0638\u0631 65% , \u062a\u062f\u0644\u064a \u0627\u0644\u062c\u0641\u0646 \u0627\u0644\u0639\u0644\u0648\u064a 50% , <\/strong><strong>\u0627\u0644\u0631\u0623\u0631\u0623\u0629 <\/strong><strong>37%<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0636\u0639\u0641 \u0641\u064a \u0627\u0644\u0633\u0645\u0639 \u0628\u062f\u0631\u062c\u0627\u062a \u0645\u062a\u0641\u0627\u0648\u062a\u0629<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u062a\u0634\u0648\u0647\u0627\u062a \u0641\u064a \u0627\u0644\u0642\u0644\u0628 :\u0642\u062f <\/strong><strong>\u062a\u062d\u062f\u062b <\/strong><strong>\u0641\u064a \u062d\u0648\u0627\u0644\u064a 25% .<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a : <\/strong><strong>\u0642\u062f \u062a\u062d\u062f\u062b \u0641\u064a <\/strong><strong>85 % \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a , \u0645\u062b\u0644 \u0627\u0644\u0627\u0631\u062a\u062c\u0627\u0639 \u0627\u0644\u0645\u0639\u062f\u064a \u0625\u0644\u0649 \u0627\u0644\u0645\u0631\u064a\u0621 \u0627\u0644\u062a\u064a \u0627\u0639\u0631\u0627\u0636\u0647\u0627 : \u062d\u0631\u0642\u0627\u0646 \u0627\u0644\u0645\u0639\u062f\u0629 , \u0648 \u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0634\u0647\u064a\u0629 <\/strong><strong>\u0648 \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062a\u0646\u0641\u0633.<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0627\u0644\u0628\u0639\u0636 \u0642\u062f \u064a\u0643\u0648\u0646 \u0644\u062f\u064a\u0647 \u062a\u0634\u0648\u0647\u0627\u062a \u0627\u062e\u0631\u0649 \u0645\u062b\u0644 \u0634\u0642 \u0627\u0644\u062d\u0646\u0643 \u0623\u0648 \u062a\u0634\u0648\u0647\u0627\u062a \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0628\u0648\u0644\u064a \u0623\u0648 \u0639\u062f\u0645 \u0646\u0632\u0648\u0644 \u0627\u0644\u062e\u0635\u064a\u062a\u064a\u0646 <\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0628\u0639\u0636 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0642\u062f \u064a\u0638\u0647\u0631 \u0639\u0644\u064a\u0647\u0627 \u062a\u0634\u0646\u062c\u0627\u062a<\/strong><\/span><\/li>\n<li><span style=\"color: #000000;\"><strong>\u0645\u0634\u0627\u0643\u0644 \u0633\u0644\u0648\u0643\u064a\u0629\u00a0 \u0643\u0625\u064a\u0630\u0627\u0621 \u0627\u0644\u0646\u0641\u0633 \u0648 <\/strong><strong>\u0641\u0631\u0637 \u0627\u0644\u062d\u0631\u0643\u0629 \u0648 \u062a\u0634\u062a\u062a \u0627\u0644\u0627\u0646\u062a\u0628\u0627\u0647, \u0642\u062f <\/strong><strong>\u062a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u0646\u0645\u0648 \u0648 \u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0648 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a<\/strong><\/span><\/li>\n<\/ul>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong><u>\u00a0\u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0643\u0644\u0627\u0633\u064a\u0643\u064a :<\/u><\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>\u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u0638\u0627\u0647\u0631\u0629 \u0644\u0645\u0646 \u0644\u062f\u064a\u0647\u0645 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u0643\u0644\u0627\u0633\u064a\u0643\u064a \u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u062a\u0643\u0648\u0646 \u0643\u0645\u0627 \u064a\u0644\u064a\u00a0 \u0645\u0639 \u0627\u0644\u0639\u0644\u0645 \u0627\u0646\u0647 \u0644\u0627 \u064a\u0634\u062a\u0631\u0637 \u0623\u0646 \u062a\u0638\u0647\u0631 \u0639\u0644\u0649 \u062c\u0645\u064a\u0639 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 : <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211;\u00a0 <\/strong><strong>\u0645\u0644\u0627\u0645\u062d \u0628\u0627\u0644\u0648\u062c\u0647 \u0645\u0645\u064a\u0632\u0647 \u0648 \u0645\u062a\u0634\u0627\u0628\u0647\u0629 \u0628\u064a\u0646\u0647\u0645 \u062a\u0638\u0647\u0631 \u0641\u064a \u062d\u0648\u0627\u0644\u064a <\/strong><strong>\u00a095% \u0645\u0646 \u0627\u0644\u0623\u0641\u0631\u0627\u062f.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; <\/strong><strong>\u0642\u0635\u0631 \u0641\u064a \u0627\u0644\u0637\u0648\u0644 \u0648 \u0646\u0642\u0635 \u0641\u064a \u0627\u0644\u0648\u0632\u0646 \u0648 \u0645\u062d\u064a\u0637 \u0627\u0644\u0631\u0623\u0633 \u062d\u064a\u062b \u064a\u0643\u0648\u0646 <\/strong><strong>\u0627\u0644\u0637\u0648\u0644 \u0648 \u0627\u0644\u0648\u0632\u0646 \u0648\u0645\u062d\u064a\u0637 \u0627\u0644\u0631\u0623\u0633 \u0627\u0642\u0644 \u0645\u0646 \u0627\u0644\u0645\u0626\u0648\u064a \u0627\u0644\u062e\u0627\u0645\u0633 \u0639\u0644\u0649 \u0627\u0644\u0631\u0633\u0645 \u0627\u0644\u0628\u064a\u0627\u0646\u064a \u0644\u0644\u0646\u0645\u0648 <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u062a\u0634\u0648\u0647\u0627\u062a \u0641\u064a <\/strong><strong>\u0627\u0644\u0623\u0637\u0631\u0627\u0641 \u0627\u0644\u0639\u0644\u064a\u0627<\/strong><strong> \u0645\u062b\u0644 : \u0627\u0635\u0627\u0628\u0639 \u0646\u0627\u0642\u0635\u0629 ,<\/strong><strong>\u0623\u0648 \u0642\u0635\u0631 \u0641\u064a \u0627\u0644\u064a\u062f\u064a\u0646 \u0648 \u0627\u0644\u062a\u0635\u0627\u0642 \u0639\u0638\u0645\u0629 \u0627\u0644\u0631\u0627\u0639 \u0645\u0639 \u0627\u0644\u0633\u0627\u0639\u062f \u0639\u0646\u062f \u0645\u0641\u0635 \u0627\u0644\u0643\u0648\u0639 \u0648 \u0642\u062f \u062a\u062a\u0637\u0644\u0628 \u062a\u062f\u062e\u0644 \u062c\u0631\u0627\u062d\u064a \u0644\u0641\u0635\u0644\u0647\u0627.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211;\u00a0 \u0634\u0639\u0631 <\/strong><strong>\u0627\u0644<\/strong><strong>\u062c\u0633\u0645 \u0648 <\/strong><strong>\u0627\u0644<\/strong><strong>\u0631\u0623\u0633 \u0643\u062b\u064a\u0641 <\/strong><strong>\u0648\u063a\u0632\u064a\u0632 \u0648 \u0642\u062f \u064a\u0645\u062a\u062f \u0627\u0644\u0649 \u0627\u0644\u062c\u0628\u0647 \u0648 \u0627\u0645\u0627\u0645 \u0627\u0644\u0623\u0630\u0646\u064a\u0646.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0625\u0639\u0627\u0642\u0629 \u0627\u0644\u0630\u0647\u0646\u064a\u0629\u00a0 : \u0645\u0639\u062f\u0644 \u0627\u0644\u0630\u0643\u0627\u0621 \u064a\u062a\u0631\u0627\u0648\u062d \u0628\u064a\u0646 30-86 <\/strong><strong>\u0641\u064a <\/strong><strong>\u0645\u0639\u0638\u0645 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 <\/strong><strong>\u0645\u0646 \u0630\u0648\u064a<\/strong><strong> \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u00a0<\/strong><strong>\u0627\u0644\u0643\u0644\u0627\u0633\u064a\u0643\u064a<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0648 \u0623\u064a\u0636\u0627\u064b <\/strong><strong>\u0636\u0639\u0641 \u0641\u064a \u0627\u0644\u062a\u0648\u0627\u0635\u0644 \u0627\u0644\u0644\u063a\u0648\u064a \u0648 \u0627\u0644\u0643\u0644\u0627\u0645<\/strong><strong> .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; <\/strong><strong>\u0628\u0639\u0636 \u0623\u0639\u0631\u0627\u0636 <\/strong><strong>\u0627\u0644\u062a\u0648\u062d\u062f \u0648 \u0627\u0644\u0633\u0644\u0648\u0643 <\/strong><strong>\u0627\u064a\u0630\u0627\u0621 \u0627\u0644\u0646\u0641\u0633 <\/strong><strong>: \u0628\u0639\u0636 \u0645\u0646\u0647\u0645 \u0642\u062f \u062a\u0638\u0647\u0631 \u0639\u0644\u064a\u0647 \u0627\u0639\u0631\u0627\u0636 \u0627\u0644\u0631\u0641\u0636 \u0644\u0644\u0623\u062e\u0631\u064a\u0646 \u0648 \u0631\u0641\u0636 \u0644\u0644\u062a\u0648\u0627\u0635\u0644 \u0648 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639\u064a\u0629 \u0623\u0648 \u0627\u0644\u0627\u062a\u0635\u0627\u0644 \u0627\u0644\u062c\u0633\u062f\u064a , <\/strong><strong>\u0648 \u0642\u062f \u064a\u0638\u0647\u0631 \u0639\u0644\u064a\u0647\u0645 \u0633\u0644\u0648\u0643\u064a\u0627\u062a \u0627\u062e\u0631\u0649 \u0628\u0633\u0628\u0628 \u0627\u0644\u062a\u0630\u0645\u0631 \u0648 <\/strong><strong>\u0627\u0644\u0625\u062d\u0628\u0627\u0637 \u0648 \u0639\u062f\u0645 \u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0643\u0645\u0627 \u062a\u0638\u0647\u0631 \u0639\u0644\u0649 \u0628\u0639\u0636\u0647\u0645 \u062a\u0641\u0648\u062a \u0641\u064a \u062f\u0631\u062c\u0629 \u062d\u0631\u0627\u0631\u0629 \u0627\u0644\u062c\u0633\u0645 \u0648 \u0636\u0639\u0641 \u0627\u062d\u0633\u0627\u0633\u0647\u0645 \u0644\u0644\u0623\u0644\u0645 \u0639\u0646\u062f \u062d\u062f\u0648\u062b \u062c\u0631\u0648\u062d \u0644\u0647\u0645.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a: \u0627\u0644\u0627\u0631\u062a\u062c\u0627\u0639 \u0627\u0644\u0645\u0639\u062f\u064a \u0644\u0644\u0645\u0631\u064a\u0621 \u0645\u0646 \u0627\u0634\u0647\u0631\u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u062a\u064a \u064a\u0639\u0627\u0646\u064a \u0645\u0646\u0647\u0627 \u0630\u0648\u064a \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u0648 \u0642\u062f \u062a\u0643\u0648\u0646 \u0647\u064a \u0627\u062d\u062f \u0627\u0644\u0627\u0633\u0628\u0627\u0628 \u0627\u0644\u062a\u064a \u062a\u062c\u0639\u0644 \u0627\u0644\u0637\u0641\u0644 \u064a\u0634\u0639\u0631 \u0628\u0627\u0644\u0627\u0645 \u0645\u0632\u0645\u0646\u0647 \u0648 \u0642\u0644\u0642 \u0648 \u0639\u062f\u0645 \u0627\u0631\u062a\u064a\u0627\u062d\u060c \u0643\u0645\u0627 \u0627\u0646\u0647\u0627 \u0645\u0646 \u0627\u0644\u0627\u0633\u0628\u0627\u0628 \u0627\u0644\u0631\u0626\u064a\u064a\u064a\u0633\u0629\u00a0\u00a0 \u0627\u0644\u062a\u064a \u062a\u0632\u064a\u062f \u0645\u0646 \u062d\u0627\u0644\u062a \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0635\u062f\u0631 \u0648 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u062a\u0646\u0641\u0633\u064a\u0629 .\u0648 \u0642\u062f \u062a\u0638\u0647\u0631 \u0627\u0644\u0627\u0639\u0631\u0627\u0636 \u0639\u0644\u0649 \u0634\u0643\u0644 \u062a\u0631\u062c<\/strong><\/p>\n<p><strong style=\"color: #339966; text-align: right;\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-567 aligncenter\" src=\"http:\/\/werathah.com\/birth-defects\/wp-content\/uploads\/2018\/03\/corneliadelange2.jpg\" alt=\"\" width=\"796\" height=\"563\" \/><\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u064a\u0639 \u0644\u0644\u062d\u0644\u064a\u0628 \u0627\u0648 \u0642\u064a\u0621 \u0645\u062a\u0643\u0631\u0631 \u0623\u0648 \u0636\u0639\u0641 \u0641\u064a \u0627\u0644\u0631\u0636\u0627\u0639\u0629 .\u0643\u0645\u0627 \u0623\u0646 \u0642\u062f \u064a\u0635\u0627\u0628 \u0628\u0639\u0636\u0647\u0645 \u0628\u062a\u0636\u064a\u0642 \u0641\u064a \u0641\u0648\u0647\u0629 \u0627\u0644\u0645\u0639\u062f\u0629 \u0627\u0644\u0633\u0641\u0644\u064a \u0628\u0645\u0627 \u064a\u0639\u0631\u0641 \u0628 (<\/strong><strong>Pyloric stenosis<\/strong><strong>)\u0648 \u0627\u0644\u062a\u064a \u062a\u0633\u062a\u062f\u0639\u064a \u062a\u062f\u062e\u0644 \u062c\u0631\u0627\u062d\u064a.<\/strong><\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0635\u062d\u064a\u0629 \u0627\u0644\u0623\u062e\u0631\u0649 :<\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211;\u00a0 \u062a\u0634\u0648\u0647\u0627\u062a \u0641\u064a \u0627\u0644\u0642\u0644\u0628 \u00a0\u0641\u064a \u062d\u0648\u0627\u0644\u064a 25% \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a \u0641\u064a \u062d\u0648\u0627\u0644\u064a 85%<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0635\u0631\u0639 \u0641\u064a \u062d\u0648\u0627\u0644\u064a 25%<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0636\u0639\u0641 \u0627\u0644\u0633\u0645\u0639 ( \u0635\u0645\u0645 \u0641\u064a \u0627\u0644\u0639\u0635\u0628 \u0641\u064a \u062d\u0648\u0627\u0644\u064a \u00a080% ) \u0648 \u0628\u0639\u0636\u0647\u0645 \u0634\u062f\u064a\u062f.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0628\u0648\u0644\u064a \u0648 \u0627\u0644\u062a\u0646\u0627\u0633\u0644\u064a <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u0646\u0638\u0631 \u0641\u062d\u0648\u0627\u0644\u064a 60 \u0645\u0646\u0647\u0645 \u0644\u062f\u064a\u0647 \u0642\u0635\u0631 \u0646\u0638\u0631 \u0648 50 \u0646\u0632\u0648\u0644 \u0641\u064a \u0627\u0644\u062c\u0641\u0646\u064a\u0646 <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u0645\u0633\u0627\u0644\u0643 \u0627\u0644\u0628\u0648\u0644\u064a\u0629 : 73% \u0642\u062f \u064a\u0643\u0648\u0646 \u0644\u062f\u064a\u0647\u0645 \u0639\u062f\u0645 \u0646\u0632\u0648\u0644 \u0644\u0644\u062e\u0635\u064a\u062a\u064a\u0646 \u0648 \u062d\u0648\u0627\u0644 57% \u0639\u062f\u0645 \u0627\u0643\u062a\u0645\u0627\u0644 \u0627\u0644\u0627\u0639\u0636\u0627\u0621 \u0627\u0644\u062a\u0646\u0627\u0633\u0644\u064a\u0629 .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0642\u062f \u064a\u0643\u0648\u0646 \u0647\u0646\u0627\u0643 \u062a\u0627\u062e\u0631 \u0641\u064a \u0638\u0647\u0648\u0631 \u0627\u0644\u0628\u0644\u0648\u063a \u0648\u0644\u0643\u0646 \u0627\u0643\u062b\u064a\u0631 \u0645\u0646\u0647\u0645 \u064a\u0628\u0644\u063a \u0639\u0646\u062f \u0633\u0646 13\u0639\u0627\u0645.<\/strong><strong><u>\u00a0<\/u><\/strong><\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong><u>\u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062e\u0641\u064a\u0641:<\/u><\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>\u0645\u0646 \u0644\u062f\u064a\u0647 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062e\u0641\u064a\u0641 \u0641\u0627\u0646 \u0627\u0644\u0627\u0639\u0631\u0627\u0636 \u0627\u0644\u062a\u064a \u0630\u0643\u0631\u0646\u0627\u0647\u0627 \u0642\u062f \u062a\u0643\u0648\u0646 \u0645\u0648\u062c\u0648\u062f\u0647 \u0648\u0644\u0643\u0646 \u0628\u062f\u0631\u062c\u0629 \u062e\u0641\u064a\u0641\u0629 \u0643\u0630\u0644\u0643 \u0642\u062f\u0631\u0627\u062a\u0647\u0645 \u0627\u0644\u062a\u0646\u0645\u0648\u064a\u0629 \u062a\u0643\u0648\u0646 \u0627\u0641\u0636\u0644 \u0645\u0645\u0646 \u0644\u062f\u064a\u0647\u0645 \u0627\u0644\u0648\u0639 \u0627\u0644\u0643\u0644\u0627\u0633\u064a\u0643\u064a \u0643\u0627\u0644\u0642\u062f\u0631\u0627\u062a \u0627\u0644\u0639\u0642\u0644\u064a\u0629 \u0648 \u062a\u0623\u062b\u064a\u0631\u0647\u0627 \u0639\u0644\u0649 \u0627\u0644\u0623\u0637\u0631\u0627\u0641.<\/strong><\/p>\n<h1 style=\"text-align: right;\"><strong><br \/>\n<span style=\"color: #33cccc;\">\u0627\u0644\u0623\u0633\u0628\u0627\u0628 :<\/span><\/strong><\/h1>\n<p style=\"text-align: right;\"><strong>\u0641\u064a \u0627\u0644\u0633\u0627\u0628\u0642 \u0644\u0645 \u064a\u0643\u0646 \u0645\u0639\u0631\u0648\u0641 \u0633\u0628\u0628 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u0644\u0643\u0646 \u0645\u0639 \u062a\u0642\u062f \u0627\u0644\u0637\u0628 \u0648\u062c\u062f \u0627\u0646 \u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0645\u0646 \u0644\u062f\u064a\u0647\u0645 \u0647\u0630\u0647 \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u064a\u0643\u0648\u0646 \u0627\u0644\u0633\u0628\u0628 \u062e\u0644\u0644 \u0641\u064a \u0627\u062d\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0648 \u0642\u062f \u062a\u0645 \u0627\u0643\u062a\u0634\u0627\u0641 \u062d\u0648\u0627\u0644\u064a 5 \u062c\u064a\u0646\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629 \u0642\u062f \u062a\u062a\u0633\u0628\u0628 \u0641\u064a \u0638\u0647\u0648\u0631 \u0647\u0630\u0647 \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0644 \u0637\u0641\u0644 \u0645\u0635\u0627\u0628 \u0642\u062f \u064a\u0643\u0648\u0646 \u0644\u062f\u064a\u0647 \u062e\u0644\u0644 (\u0637\u0641\u0631\u0629) \u0641\u064a \u0627\u062d\u062f \u0647\u0630\u0627 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0648 \u0644\u064a\u0633 \u062c\u0645\u064a\u0639\u0647\u0627 \u062f\u0641\u0639\u0647 \u0648\u0627\u062d\u062f\u0647. \u0648 \u0647\u0630\u0647 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0647\u064a \u00a0<\/strong><strong>(<\/strong><strong><a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/NIPBL\" target=\"_blank\" rel=\"noopener\">NIPBL<\/a><\/strong><strong>\u00a0<a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/SMC1A\" target=\"_blank\" rel=\"noopener\">SMC1A<\/a>,\u00a0<a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/HDAC8\" target=\"_blank\" rel=\"noopener\">HDAC8<\/a>,\u00a0<a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/RAD21\" target=\"_blank\" rel=\"noopener\">RAD21<\/a>, and\u00a0<a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/SMC3\" target=\"_blank\" rel=\"noopener\">SMC3<\/a>.<\/strong><strong>)\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0\u0648 \u064a\u0639\u062a\u0628\u0631 \u0627\u0644\u062c\u064a\u0646 \u0627\u0644\u0645\u0633\u0645\u0649 \u0628\u064a\u0646 \u0646\u064a\u0628\u0644 (NIPBL\u00a0) \u0647\u0648 \u0627\u0634\u0647\u0631\u0647\u0627 \u0648 \u064a\u0635\u064a\u0628 \u062d\u0648\u0627\u0644\u064a<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0647\u0648 \u0627\u0634\u0647\u0631\u0647\u0627 \u0648 \u064a\u0643\u0648\u0646 \u0647\u0648 \u0627\u0644\u0633\u0628\u0628 \u0641\u064a \u062d\u0648\u0627\u0644\u064a 50% \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0645\u0635\u0627\u0628\u0629 <\/strong><strong>\u00a0 .\u0648 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u062e\u0631\u0649 \u0627\u0642\u0644 \u0627\u0646\u062a\u0634\u0627\u0631\u0627\u064b. \u0643\u0645\u0627 \u0623\u0646 \u062d\u0648\u0627\u0644\u064a 30% \u0645\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0644\u0645 \u064a\u0639\u0631\u0641 \u0628\u0639\u062f \u0627\u0633\u0628\u0627\u0628\u0647\u0627 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0648 \u0642\u062f \u062a\u0643\u0648\u0646 \u0628\u0633\u0628\u0628 \u062e\u0644\u0644 \u0641\u064a \u0627\u0644\u0643\u0631\u0648\u0645\u0648\u0633\u0648\u0645\u0627\u062a \u0623\u0648 \u0628\u0633\u0628\u0628 \u062e\u0644\u0644 \u0641\u064a \u062c\u064a\u0646\u0627\u062a \u0627\u062e\u0631\u0649 \u0644\u0645 \u062a\u0643\u062a\u0634\u0641 \u0628\u0639\u062f.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0648 \u0641\u064a\u0645\u0627 \u064a\u0628\u062f\u0648\u0627 \u0641\u0627\u0646 \u0647\u0630\u0647 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0644\u0647\u0627 \u0639\u0644\u0627\u0642\u0629 \u0641\u064a \u062a\u0643\u0648\u0646 \u062c\u0633\u0645 \u0628\u0631\u0648\u062a\u064a\u0646\u064a \u064a\u0633\u0645\u0649\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>(cohesin complex) \u0648 \u0644\u0647 \u0627\u0647\u0645\u064a\u0629 \u0641\u064a \u062e\u0644\u0642 \u0627\u0644\u0627\u0646\u0633\u0627\u0646 \u0648 \u0627\u0644\u0646\u0645\u0648\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u0637\u0631\u064a\u0642\u0629 \u0627\u0646\u062a\u0642\u0627\u0644 \u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0636<\/strong><\/span><\/h1>\n<p>&nbsp;<\/p>\n<p style=\"text-align: right;\"><strong>\u0627\u0644\u0645\u0631\u0636 \u0643\u0645\u0627 \u0630\u0643\u0631\u0646\u0627 \u064a\u0635\u064a\u0628\u00a0 \u0627\u0644\u0630\u0643\u0648\u0631 \u0648 \u0627\u0644\u0625\u0646\u0627\u062b \u0628\u0634\u0643\u0644 \u0645\u062a\u0633\u0627\u0648\u064a \u0643\u0645\u0627 \u0623\u0646\u0647 \u064a\u0635\u064a\u0628 \u0643\u0644 \u0627\u0644\u0623\u0639\u0631\u0627\u0642 \u0648\u0627\u0644\u0645\u062c\u062a\u0645\u0639\u0627\u062a \u0648 \u0647\u0648 \u0641\u064a \u0627\u0644\u063a\u0627\u0644\u0628 \u0646\u062a\u064a\u062c\u0629 \u0644\u0637\u0641\u0631\u0629 \u0648\u0631\u0627\u062b\u064a\u0629 \u0641\u064a \u0627\u062d\u062f \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0627\u0644\u062a\u064a \u0630\u0643\u0631\u0646\u0627\u0647\u0627 .\u0648 \u0645\u0639\u0638\u0645 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u064a\u0643\u0648\u0646\u0648\u0627 \u0647\u0645 \u0623\u0648 \u0637\u0641\u0644 \u0645\u0635\u0627\u0628 \u0641\u064a \u0627\u0644\u0639\u0627\u0626\u0644\u0629 . \u0648 \u0644\u0630\u0644\u0643 \u0647\u064a \u062a\u062d\u062f\u062b \u0641\u064a \u0627\u0644\u063a\u0644\u0628 \u0628\u0633\u0628\u0628 \u0637\u0641\u0631\u0629 \u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0648 \u062a\u0646\u062a\u0642\u0644 \u0645\u0646 \u062c\u064a\u0644 \u0627\u0644\u0649 \u0623\u062e\u0631 \u0628\u0645\u0627 \u064a\u0639\u0631\u0641 \u0628\u0627\u0644\u0648\u0631\u0627\u062b\u0629 \u0627\u0644\u0633\u0627\u0626\u062f\u0629 \u0623\u064a \u0623\u0646\u0647 \u064a\u0643\u0641\u064a \u0627\u0646 \u062a\u0643\u0648\u0646 \u0627\u062d\u062f \u0646\u0633\u062e\u062a\u064a \u0627\u0644\u062c\u064a\u0646 \u0645\u0639\u0637\u0648\u0628\u0629 \u0644\u0643\u064a \u064a\u0638\u0647\u0631 \u0627\u0644\u0645\u0631\u0636. \u0644\u0643\u0646\u0647 \u0644\u0627 \u064a\u0634\u062a\u0631\u0637 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0627\u062d\u062f \u0627\u0644\u0627\u0628\u0648\u064a\u0646 \u0645\u0635\u0627\u0628 \u0644\u0627\u0646 \u0627\u0644\u062e\u0644\u0644 \u0627\u0644\u062c\u064a\u0646\u064a \u0639\u0627\u062f\u0629 \u064a\u0643\u0648\u0646 \u0628\u0633\u0628\u0628 \u0637\u0641\u0631\u0629 \u062c\u062f\u064a\u062f\u0629 . \u0623\u0630\u0627 \u0643\u0627\u0646 \u0627\u062d\u062f \u0627\u0644\u0627\u0628\u0648\u064a\u0646 \u0645\u0635\u0627\u0628 \u0628\u0634\u0643\u0644 \u062e\u0641\u064a\u0641 \u0641\u0627\u0646 \u0627\u062d\u062a\u0645\u0627\u0644 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0627\u0635\u0627\u0628\u0629 \u0642\u062f \u062a\u0635\u0644 \u0627\u0644\u0649 50% \u0641\u064a \u0643\u0644 \u062d\u0645\u0644 .\u0644\u0630\u0644\u0643 \u0645\u0646 \u0627\u0644\u0645\u0641\u064a\u062f \u0639\u0645\u0644 \u0641\u062d\u0635 \u0644\u0644\u062c\u064a\u0646\u0627\u062a \u0644\u0644\u0637\u0641\u0644 \u0627\u0644\u0645\u0635\u0627\u0628 \u062b\u0645 \u0641\u062d\u0635 \u0627\u0644\u0627\u0628\u0648\u064a\u0646 \u0644\u0644\u062a\u0623\u0643\u062f \u0645\u0646 \u0633\u0644\u0627\u0645\u062a\u0647\u0645. \u0627\u0630\u0627 \u00a0\u0644\u0645 \u064a\u062c\u0631\u0649 \u0627\u0644\u0641\u062d\u0635 \u0648 \u0644\u0645 \u064a\u0643\u0646 \u0647\u0646\u0627\u0643 \u0637\u0641\u0644 \u0645\u0635\u0627\u0628 \u0641\u064a \u0627\u0644\u0639\u0627\u0626\u0644\u0629 \u0633\u0627\u0628\u0642\u0627\u064b\u060c 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href=\"https:\/\/ghr.nlm.nih.gov\/gene\/HDAC8\" target=\"_blank\" rel=\"noopener\">HDAC8<\/a>)\u060c\u0628\u064a\u0646\u0645\u0627 \u0627\u0644\u062c\u064a\u0646 \u0627\u0644\u0631\u0627\u0628\u0639 <\/strong><strong>\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0641\u0647\u0648 \u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u062c\u0646\u0633 \u0648\u0647\u0648 \u064a\u0635\u064a\u0628 \u0627\u0644\u0630\u0643\u0648\u0631 \u0641\u0642\u0637<\/strong><\/p>\n<p style=\"text-align: right;\"><strong> \u0648\u062a\u0646\u0642\u0644\u0647 \u0627\u0644\u0627\u0646\u0627\u062b ( \u0627\u0644\u0627\u0645\u0647\u0627\u062a) \u0648 \u0644\u0630\u0644\u0643 \u064a\u062c\u0628 \u0641\u062d\u0635 \u0627\u0644\u0623\u0645 \u0627\u0630\u0627 \u0643\u0627\u0646 \u0647\u0630\u0627 \u0627\u0644\u062c\u064a\u0646 \u0647\u0648 \u0627\u0644\u0633\u0628\u0628 \u0641\u064a \u0638\u0647\u0648\u0631 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u0627\u0644\u062a\u0634\u062e\u064a\u0635<\/strong><strong> :<\/strong><\/span><\/h1>\n<p style=\"text-align: right;\"><strong>\u064a\u062a\u0645 \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u0645\u062e\u062a\u0635 <\/strong><strong>\u062d\u0633\u0628 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062c\u0633\u0645\u064a\u0629 \u0627\u0644\u0638\u0627\u0647\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u0637\u0641\u0644 \u0648 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u062e\u0644\u0642\u064a\u0629 \u0627\u0644\u0645\u0635\u0627\u062d\u0628\u0629 \u0644\u0647\u0627 <\/strong><strong>\u0648 \u062a\u062c\u0631\u0649 \u0623\u064a\u0636\u0627\u064b \u0641\u062d\u0648\u0635\u0627\u062a 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\u0644\u0644\u0645\u062a\u0627\u0628\u0639\u0629 .\u0643\u0645\u0627 \u0642\u062f \u064a\u062d\u062a\u0627\u062c \u0627\u0644\u0637\u0641\u0644 \u0627\u0644\u0649 \u0641\u062d\u0648\u0635\u0627\u062a \u0645\u062a\u0643\u0631\u0631\u0629 \u0644\u0644\u0633\u0645\u0639 .\u0648 \u0647\u0630\u0647 \u0628\u0639\u0636 \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0644\u0644\u0645\u062a\u0627\u0628\u0639\u0629 :<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u062d\u0635 \u0627\u0644\u0639\u064a\u0646 <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u062d\u0635 \u0627\u0644\u0633\u0645\u0639<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; <\/strong><strong>\u0627\u0643\u062a\u0634\u0627\u0641<\/strong><strong> \u0623\u064a \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a \u0645\u062b\u0644 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\u063a\u0646\u064a \u0628\u0627\u0644\u0633\u0639\u0631\u0627\u062a \u0627\u0644\u062d\u0631\u0627\u0631\u064a\u0629 \u0644\u0645\u0633\u0627\u0639\u062f\u062a\u0647\u0645 \u0641\u064a \u0627\u0643\u062a\u0633\u0627\u0628 \u0627\u0644\u0648\u0632\u0646 <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0645\u0646\u0627\u0642\u0634\u0629 \u0627\u0644\u0627\u0646\u062c\u0627\u0628 \u0641\u064a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644 \u0645\u0639 \u0627\u0644\u0637\u0628\u064a\u0628 \u0648 \u0627\u0644\u0641\u062d\u0635 \u062e\u0644\u0627\u0644 \u0627\u0644\u062d\u0645\u0644 \u0627\u0630\u0627 \u0644\u0632\u0645 \u0627\u0644\u0623\u0645\u0631. \u0644\u0630\u0644\u0643 \u064a\u062d\u062a\u0627\u062c \u0627\u0644\u0637\u0641\u0644 \u0627\u0646 \u064a\u0632\u0648\u0631 \u0637\u0628\u064a\u0628 \u0627\u0644\u0648\u0631\u0627\u062b\u0629 \u0644\u0646\u0642\u0627\u0634 \u0647\u0630\u0647 \u0627\u0644\u0645\u0648\u0636\u0648\u0639 . \u00a0\u00a0\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #33cccc;\"><strong>\u062a\u0648\u0635\u064a\u0627\u062a \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0639\u0644\u0649 \u062d\u0633\u0628 \u0627\u0644\u0639\u0645\u0631 :<\/strong><\/span><\/h1>\n<h2 style=\"text-align: right;\"><span style=\"color: #339966;\"><strong>1- \u00a0\u0641\u064a \u0627\u0644\u0637\u0641\u0648\u0644\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 ( \u0645\u0646 \u0633\u0646\u0629 \u0625\u0644\u0649 8 \u0633\u0646\u0648\u0627\u062a )<\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0630\u0643\u0648\u0631 \u0627\u0644\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062a\u0623\u062e\u0631 \u0646\u0632\u0648\u0644 \u0627\u0644\u062e\u0635\u064a\u0629 \u064a\u062c\u0628 \u0627\u0646 \u064a\u0642\u0648\u0645\u0648\u0646 \u0628\u0639\u0645\u0644\u064a\u0629 \u062a\u0635\u062d\u064a\u062d \u0639\u0646\u062f \u0639\u0645\u0631 \u0627\u064418 \u0634\u0647\u0631<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u062e\u062f\u0645\u0627\u062a \u0645\u0633\u062a\u0645\u0631\u0629 \u0644\u0644\u0645\u0633\u0627\u0639\u062f\u0629 \u0641\u064a \u062a\u0637\u0648\u064a\u0631 \u0645\u0647\u0627\u0631\u0627\u062a \u0627\u0644\u062a\u0648\u0627\u0635\u0644<\/strong><strong> .\u0648 \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u062a\u0639\u0644\u064a\u0645 \u0627\u0644\u0641\u0631\u062f\u064a \u0644\u0647\u0645 \u0641\u064a \u0627\u0644\u0645\u062f\u0631\u0633\u0629 .\u064a\u0641\u064a\u062f\u0647\u0645 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0638\u064a\u0641\u064a\u00a0 \u0648\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0637\u0628\u064a\u0639\u064a . \u0643\u0645\u0627 <\/strong><strong>\u0623\u0646 \u00a0\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0644\u063a\u0629 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0642\u062f \u064a\u0643\u0648\u0646<\/strong><strong> \u0645\u0641\u064a\u062f \u0641\u064a \u062d\u0627\u0644 \u0639\u062f\u0645 \u062a\u062d\u0633\u0646 \u0627\u0644\u0646\u0637\u0642 \u0644\u0644\u062a\u0648\u0627\u0635\u0644 \u0645\u0639 \u0627\u0644\u0637\u0641\u0644 . \u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0641\u064a \u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0646\u0645\u0648 \u0639\u0646 \u0637\u0631\u064a\u0642 \u062c\u062f\u0648\u0644 \u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u062e\u0627\u0635 \u0644\u0623\u0637\u0641\u0627\u0644 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0637\u0628\u064a\u0628 \u0627\u0633\u0646\u0627\u0646 \u0645\u062a\u062e\u0635\u0635 \u0641\u064a \u0627\u0644\u062a\u0639\u0627\u0645\u0644 \u0645\u0639 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0623\u0648 \u0627\u0644\u0627\u0637\u0641\u0627\u0644 \u0630\u0648\u064a \u0627\u0644\u0627\u062d\u062a\u064a\u0627\u062c\u0627\u062a \u0627\u0644\u062e\u0627\u0635\u0629 \u0643\u0644 6 \u0623\u0634\u0647\u0631<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211;\u00a0 \u0641\u062d\u0635 \u0627\u0644\u0646\u0638\u0631 \u0633\u0646\u0648\u064a\u0627\u064b <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u062d\u0635 \u0627\u0644\u0633\u0645\u0639 \u0643\u0644 \u0633\u0646\u062a\u064a\u0646 \u0627\u0644\u0649 \u062b\u0644\u0627\u062b \u0633\u0646\u0648\u0627\u062a <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0641\u062d\u0635 \u0648 \u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0627\u0637\u0641\u0627\u0644 \u0627\u0644\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0645\u0639 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0627\u0644\u0645\u062e\u062a\u0635\u064a\u0646 \u0642\u062f\u0631 \u0627\u0644\u0625\u0645\u0643\u0627\u0646 <\/strong><\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #339966;\"><strong>2- \u0641\u064a \u0623\u0648\u0627\u062e\u0631 \u0627\u0644\u0637\u0641\u0648\u0644\u0629 ( \u0645\u0646 8 \u0633\u0646\u0648\u0627\u062a \u2013 \u0627\u0644\u0628\u0644\u0648\u063a )<\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0645\u0639 \u0637\u0628\u064a\u0628 \u062c\u0631\u0627\u062d\u0629 \u0627\u0644\u0639\u0638\u0627\u0645 \u0627\u0630\u0627 \u0628\u062f\u0623 \u064a\u0639\u0627\u0646\u064a \u0627\u0644\u0637\u0641\u0644 \u0645\u0646 \u0645\u0634\u0627\u0643\u0644 \u0641\u064a <\/strong><strong>\u0627\u0646\u0643\u0645\u0627\u0634 <\/strong><strong>\u0627\u0644\u0645\u0641\u0627\u0635\u0644 \u0623\u0648 \u0627\u0644\u0639\u0638\u0627\u0645 , \u0623\u0648 \u0627\u0644\u062c\u0646\u0641 .<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0633\u0644\u0648\u0643\u064a\u0629 \u0627\u0630\u0627 \u0628\u062f\u0623 \u0627\u0644\u0637\u0641\u0644 \u064a\u0639\u0627\u0646\u064a <\/strong><strong>\u0645\u0646 \u0623\u0639\u0631\u0627\u0636 \u0641\u0631\u0637 \u0627\u0644\u062d\u0631\u0643\u0629 \u0648 \u0636\u0639\u0641 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0623\u0648 \u0633\u0644\u0648\u0643\u064a\u0627\u062a \u00a0\u0627\u064a\u0630\u0627\u0621 \u0627\u0644\u0646\u0641\u0633 .<\/strong><strong>\u00a0<\/strong><\/p>\n<h2 style=\"text-align: right;\"><strong><br \/>\n<\/strong><span style=\"color: #339966;\"><strong>3- \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0645\u0631\u0627\u0647\u0642\u0629 ( \u0627\u0644\u0628\u0644\u0648\u063a \u2013 20 \u0633\u0646\u0629 )<\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211; \u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0641\u064a \u0627\u0644\u062f\u0639\u0645<\/strong><strong> \u0644\u062a\u062d\u0633\u064a\u0646 \u0627\u0644\u0645\u0647\u0627\u0631\u0627\u062a \u0648 \u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0641\u064a \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u062a\u0639\u0644\u064a\u0645 \u0627\u0644\u0641\u0631\u062f\u064a \u0641\u064a \u0627\u0644\u0645\u062f\u0631\u0633\u0629 \u0648 \u0627\u0644\u0628\u062f\u0621 \u0641\u064a \u062a\u062d\u0636\u064a\u0631 \u0627\u0644\u0627\u0641\u0631\u0627\u062f \u0648 \u062a\u062f\u0631\u064a\u0628\u0647\u0645 \u0648 \u062a\u0637\u0648\u064a\u0631 \u0645\u0647\u0627\u0631\u0627\u062a\u0647\u0645 \u0648 \u062a\u0623\u0647\u064a\u0644\u0647\u0645 \u0644\u0627\u0639\u0645\u0627\u0644 \u0645\u0646\u0627\u0633\u0628\u0647 \u0644\u0647\u0645 . <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0625\u0646\u0627\u062b :<\/strong><strong> \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u0639\u0646\u0627\u064a\u0629 \u0641\u064a \u0627\u0644\u0623\u0645\u0648\u0631 <\/strong><strong>\u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u062f\u0648\u0631\u0629 \u0627\u0644\u0634\u0647\u0631\u064a\u0629 \u0648 \u0627\u0644\u0645\u0634\u0627\u0643\u0644 \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 <\/strong><strong>\u0628\u0647\u0627 <\/strong><strong>.<\/strong><\/p>\n<h2 style=\"text-align: right;\"><span style=\"color: #339966;\"><strong>4- \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0628\u0644\u0648\u063a :<\/strong><\/span><\/h2>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u064a \u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0628\u0644\u0648\u063a \u064a\u062c\u0628 \u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a \u0644\u0627\u0646\u062c \u0639\u0646 \u0637\u0631\u064a\u0642 \u0641\u062d\u0635 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0648 \u062a\u062e\u0637\u064a\u0637 \u0627\u0644\u0642\u0644\u0628 \u0648 \u0641\u062d\u0635 \u0627\u0644\u062b\u062f\u064a \u0648 \u0627\u0644\u062e\u0635\u064a\u062a\u064a\u0646 \u0648 \u0627\u0644\u0628\u0631\u0648\u0633\u062a\u0627\u062a \u062a\u0628\u0639\u0627\u064b \u0644\u0644\u0642\u0648\u0627\u0639\u062f \u0627\u0644\u0637\u0628\u064a\u0629 \u0627\u0644\u0627\u0631\u0634\u0627\u062f\u064a\u0629 \u0627\u0644\u0645\u062a\u0628\u0639\u0629<\/strong><strong> .\u0648 \u062a\u0642\u062f\u064a\u0645 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u0635\u062d\u064a\u0629 \u0643\u0645\u0627 \u0647\u0648 \u0644\u0644\u0628\u0627\u0644\u063a\u064a\u0646.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; <\/strong><strong>\u0627\u0644\u0646\u0642\u0627\u0634 \u00a0<\/strong><strong>\u0645\u0639 \u0627\u0644\u0639\u0627\u0626\u0644\u0629 \u0648 <\/strong><strong>\u062d\u0648\u0644 \u00a0<\/strong><strong>\u0645\u0631\u0627\u0643\u0632 \u0627\u0644\u062a\u062f\u0631\u0628 \u0627\u0644\u0648\u0638\u064a\u0641\u064a \u0648 \u0627\u0644\u062a\u0639\u0644\u064a\u0645 \u0627\u0644\u0639\u0627\u0644\u064a , \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0646\u0641\u0633\u064a \u0636\u0631\u0648\u0631\u064a <\/strong><strong>\u0644\u0647\u0645 <\/strong><strong>\u00a0\u0627\u0630\u0627 \u0643\u0627\u0646\u0648\u0627 \u064a\u0639\u0627\u0646\u0648\u0646 <\/strong><strong>\u0645\u0646 \u0645\u0634\u0627\u0643\u0644 \u0641\u064a \u0641\u0631\u0637 \u0627\u0644\u062d\u0631\u0643\u0629 \u0648 \u062a\u0634\u062a\u062a \u0627\u0644\u0627\u0646\u062a\u0628\u0627\u0647 <\/strong><strong>\u0648 \u00a0\u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u0648\u0633\u0648\u0627\u0633 \u0627\u0644\u0642\u0647\u0631\u064a \u0648 \u0627\u0644\u0627\u0643\u062a\u0626\u0627\u0628 \u0648 \u0633\u0644\u0648\u0643<\/strong><strong> \u0627\u064a\u0630\u0627\u0621 \u0627\u0644\u0646\u0641\u0633.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u062d\u0635 \u0647\u0634\u0627\u0634\u0629 \u0627\u0644\u0639\u0638\u0627\u0645 \u0628\u0648\u0627\u0633\u0637\u0629 \u062c\u0647\u0627\u0632 \u0642\u064a\u0627\u0633 \u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0639\u0638\u0645 <\/strong><\/p>\n<p style=\"text-align: right;\"><strong>&#8211; \u0641\u062d\u0635 \u0627\u0644\u0627\u0633\u0646\u0627\u0646 \u064a\u062c\u0628 \u0627\u0646 \u064a\u0643\u0648\u0646 \u0643\u0644 4 -6 \u0634\u0647\u0648\u0631<\/strong> <strong><br \/>\n<\/strong><strong>\u0627\u0644\u0648\u0642\u0627\u064a\u0629<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0627\u0630\u0627 \u0643\u0627\u0646 <\/strong><strong>\u0627\u0644\u0641\u062d\u0635 <\/strong><strong>\u0627\u0644\u062c\u064a\u0646\u064a \u0644\u0644\u0648\u0627\u0644\u062f\u064a\u0646 <\/strong><strong>\u0633\u0644\u064a\u0645 <\/strong><strong>\u0641\u0647\u0630\u0627 \u064a\u0639\u0646\u064a \u0646\u0633\u0628\u0629 \u062d\u062f\u0648\u062b \u0627\u0644\u0637\u0641\u0631\u0629 \u0641\u064a \u0627\u0644\u062d\u0645\u0644 \u0627\u0644\u0645\u0642\u0628\u0644 \u0627\u0642\u0644 \u0645\u0646 1% <\/strong><strong>.\u0648 \u0644\u064a\u0633 \u0647\u0646\u0627\u0643 \u0623\u064a \u062a\u0648\u0635\u064a\u0627\u062a \u062e\u0627\u0635\u0629 \u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u062d\u0645\u0644 \u0627\u0644\u0642\u0627\u062f\u0645 <\/strong><strong>. \u0623\u0645\u0627 \u00a0\u0641\u064a \u062d\u0627\u0644\u0629 \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 <\/strong><strong>\u0637\u0641\u0631\u0629 <\/strong><strong>\u062c\u064a\u0646\u064a\u0629 <\/strong><strong>\u0644\u062f\u0649 <\/strong><strong>\u0623\u062d\u062f \u0627\u0644\u0648\u0627\u0644\u062f\u064a\u0646<\/strong><strong> \u0641\u0627\u062d\u062a\u0645\u0627\u0644 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0627\u0635\u0627\u0628\u0629 \u0641\u064a \u0643\u0644 \u062d\u0645\u0644 \u0642\u062f \u062a\u0635\u0644 \u0627\u0644\u0649 \u00a0<\/strong><strong>50% .<\/strong><strong>\u0648 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0642\u062f \u064a\u062a\u0648\u0641\u0631 \u0641\u062d\u0635 \u0644\u0644\u062c\u064a\u0646\u064a\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u062d\u0645\u0644 \u0627\u0648 \u0639\u0645\u0644 \u0627\u0644\u0641\u062d\u0635 \u0627\u0644\u0648\u0631\u0627\u062b\u064a \u0642\u0628\u0644 \u0627\u0644\u063a\u0631\u0632 \u0648 \u0643\u0630\u0644\u0643 \u0641\u062d\u0635 \u0628\u0642\u064a\u0629 \u0627\u0641\u0631\u0627\u062f <\/strong><strong>\u0627\u0644\u0639\u0627\u0626\u0644\u0629 \u0627\u0644\u0627\u062e\u0631\u064a\u0646.\u00a0\u00a0\u00a0\u00a0 <\/strong><\/p>\n<p style=\"text-align: right;\">\n<h1 style=\"text-align: right;\"><span style=\"color: #ff0000;\"><strong>\u0627\u0644\u0627\u0633\u0639\u0627\u0641\u0627\u062a<\/strong><\/span><\/h1>\n<p style=\"text-align: right;\"><strong>\u0644\u064a\u0633 \u0647\u0646\u0627\u0643 \u062e\u0637\u0629 \u0625\u0633\u0639\u0627\u0641\u064a\u0647 \u0637\u0628\u064a\u0629 \u064a\u062d\u062a\u0627\u062c\u0647\u0627 \u0627\u0641\u0631\u0627\u062f \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a\u0644\u0627\u0646\u062c .\u0648 \u0628\u0634\u0643\u0644 \u0639\u0627\u0645 \u062a\u062d\u062f\u062f \u0627\u0644\u062e\u0637\u0637 \u0627\u0644\u0625\u0633\u0639\u0627\u0641\u064a\u0647 \u0628\u0634\u0643\u0644 \u0641\u0631\u062f\u064a \u062d\u0633\u0628 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u062a\u064a \u064a\u0642\u062f\u0645\u0647\u0627 \u0627\u0644\u0648\u0627\u0644\u062f\u064a\u0646 . \u0648 \u0646\u062a\u064a\u062c\u0629 \u0644\u0644\u0635\u0639\u0648\u0628\u0627\u062a \u0627\u0644\u0639\u0642\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u0644\u062f\u064a\u0647\u0645 \u0645\u0646 \u0627\u0644\u0645\u0647\u0645 \u0627\u0644\u0627\u0646\u062a\u0628\u0627\u0647 \u0627\u0644\u0649 \u0642\u062f\u0631\u062a\u0647\u0645 \u0644\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u0627\u0645\u0648\u0631 \u0627\u0644\u062e\u0637\u0631\u0629 \u062e\u0627\u0635\u0629 \u0645\u0639 \u0627\u062d\u062a\u0645\u0627\u0644 \u0648\u062c\u0648\u062f \u0645\u0634\u0627\u0643\u0644 \u0628\u0627\u0644\u0646\u0638\u0631 \u0648 \u0627\u0644\u0633\u0645\u0639. \u0648\u0644\u0630\u0644\u0643 \u0645\u0646\u00a0\u00a0 \u0627\u0644\u0645\u0647\u0645 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0627\u0644\u0645\u0643\u0627\u0646 \u0627\u0645\u0646 \u0645\u0646 \u062d\u0648\u0644\u0647 \u0623\u0645\u0646.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u062a\u062d\u062a\u0627\u062c \u0627\u0644\u0645\u062f\u0631\u0633\u0629 \u062a\u0642\u064a\u064a\u0645 \u0648 \u062a\u062d\u062f\u064a\u062b \u0645\u0639\u0644\u0648\u0645\u0627\u062a\u0647\u0627 \u0639\u0646 \u0627\u0644\u0637\u0641\u0644 \u0635\u062d\u064a\u0627 \u0648\u0627\u0636\u0627\u0641\u0629 \u062e\u0637\u0629 \u0635\u062d\u064a\u0629 \u0627\u0633\u0639\u0627\u0641\u064a\u0647 \u0627\u0630\u0627 \u0644\u0632\u0645 \u0627\u0644\u0623\u0645\u0631 \u0648 \u064a\u062a\u0645 \u062a\u062e\u0635\u064a\u0635 \u0634\u062e\u0635 \u0628\u0627\u0644\u063a \u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0627\u0644\u0637\u0641\u0644 \u0644\u0645\u0633\u0627\u0639\u062f\u062a\u0647 \u0644\u0643\u064a \u064a\u0643\u0648\u0646 \u0641\u064a \u0627\u0645\u0627\u0646 \u0648 \u0628\u0639\u064a\u062f \u0639\u0646 \u0627\u0644\u0645\u062e\u0627\u0637\u0631 \u0641\u064a \u0627\u0644\u0645\u062f\u0631\u0633\u0629.<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #ff0000;\"><strong>\u0627\u0644\u0645\u0631\u0627\u062c\u0639 :<\/strong><\/span><\/h1>\n<p style=\"text-align: right;\"><strong>\u0645\u0648\u0642\u0639 \u0627\u0644\u0648\u0631\u0627\u062b\u0629 \u0627\u0644\u0637\u0628\u064a\u0629<\/strong><strong>\u00a0<\/strong><\/p>\n<p style=\"text-align: right;\"><strong><a href=\"https:\/\/ghr.nlm.nih.gov\/condition\/cornelia-de-lange-syndrome#diagnosis\" target=\"_blank\" rel=\"noopener\">https:\/\/ghr.nlm.nih.gov\/condition\/cornelia-de-lange-syndrome#diagnosis<\/a><\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><strong><a href=\"http:\/\/www.cdlsworld.org\/xwiki\/bin\/view\/CdLSWorld\/TreatmentGuidelinesPreventiveCare\" target=\"_blank\" rel=\"noopener\">http:\/\/www.cdlsworld.org\/xwiki\/bin\/view\/CdLSWorld\/TreatmentGuidelinesPreventiveCare<\/a><\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u0645\u0648\u0627\u0642\u0639 \u0637\u0628\u064a\u0629 \u0645\u062a\u0639\u062f\u062f\u0629<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0<\/strong><\/p>\n<h1 style=\"text-align: right;\"><span style=\"color: #ff0000;\">\u062a\u0623\u0644\u064a\u0641<\/span><\/h1>\n<h1 style=\"text-align: right;\"><strong>\u062f. \u0623\u0633\u0645\u0627\u0621 \u0645\u0637\u0646\u064a \u0627\u0644\u0645\u0637\u064a\u0631\u064a<\/strong><\/h1>\n<h1 style=\"text-align: right;\"><strong>\u0645\u0631\u0627\u062c\u0639\u0629 \u062f.\u0639\u0628\u062f\u0627\u0644\u0631\u062d\u0645\u0646 \u0641\u0627\u064a\u0632 \u0627\u0644\u0633\u0648\u064a\u062f<\/strong><\/h1>\n<p>&nbsp;<\/p>\n<h2 style=\"text-align: right;\"><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0643\u0648\u0631\u0646\u064a\u0644\u064a\u0627 \u062f\u064a\u0644\u0627\u0646\u062c Cornelia De Lange\u00a0 Syndrome \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0637\u0628\u064a\u0629 \u0627\u0633\u0645\u0627\u0621 \u0645\u062a\u0631\u0627\u062f\u0641\u0629 &#8211; \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u0627\u0644\u0634\u0639\u0631 \u0627\u0644\u0643\u062b\u064a\u0641 Bushy Syndrome\u00a0 &#8211; \u0627\u0642\u0632\u0627\u0645 \u0627\u0645\u0633\u062a\u0631\u062f\u0627\u0645. Amsterdam dwarfism \u00a0 \u0641\u064a \u0639\u0627\u0645 1916\u0645 \u0646\u0634\u0631 \u0627\u0644\u0637\u0628\u064a\u0628 \u0627\u0644\u0623\u0644\u0645\u0627\u0646\u064a \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0628\u0631\u0627\u0634\u0645\u0627\u0646 ( Brachmann )\u0648 \u0627\u0644\u0630\u064a \u0639\u0627\u0634 \u0628\u064a\u0646 \u0639\u0627\u0645\u064a (1888-1969 ) \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0639\u0646 \u00a0\u0634\u0627\u0628 \u0641\u064a \u064a\u0628\u0644\u063a 19 \u0639\u0627\u0645 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u00a0\u0628\u0645\u0644\u0627\u0645\u062d \u0645\u0645\u064a\u0632\u0629 . \u062c\u0627\u0621 \u0645\u0646 \u0628\u0639\u062f\u0647 &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[68],"tags":[],"class_list":["post-11908","post","type-post","status-publish","format-standard","hentry","category-cornelia-de-lange"],"_links":{"self":[{"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/posts\/11908","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/comments?post=11908"}],"version-history":[{"count":4,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/posts\/11908\/revisions"}],"predecessor-version":[{"id":12051,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/posts\/11908\/revisions\/12051"}],"wp:attachment":[{"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/media?parent=11908"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/categories?post=11908"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.werathah.com\/special\/wp-json\/wp\/v2\/tags?post=11908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}